Which of the Great Lakes lies entirely within the United States?

Which city is home to the Johns Hopkins Hospital and the Inner Harbor? Which river forms much of the border between Texas and Mexico? Which river forms the border between Oklahoma and Texas for much of its length? Which river forms much of the border between Oregon and Washington? What is the name of the mountain range that runs through the eastern United States? What is the name of the mountain range that includes Mount Rainier and Mount Hood? Who was the wife of George Washington? Which First Lady famously saved a portrait of George Washington when the British burned the White House?