In which TV series is John Locke a main character?

Who played Jack Shephard in 'Lost'? Who played Kate Austen in 'Lost'? In which TV series is Kate Austen a main character? Who played John Locke in 'Lost'? Who played Sawyer in 'Lost'? In which TV series is Sawyer a main character? Who played Susan Mayer in 'Desperate Housewives'? In which TV series is Susan Mayer a main character?