Based on the clue 'a sledgehammer to this insulin producing organ the...', what is the answer?

Based on the clue 'a slangy term for a baseball doubleheader', what is the answer? What is associated with: a slave called isabella at birth adopted this unusual name in 1843 became an itinerant preache… Based on the clue 'a slaveowners son becomes an abolitionist in a dif...', what is the answer? Based on the clue 'a sled weighing no more than 50 pounds a steep hil...', what is the answer? Based on the clue 'a sleek country rock sound helped this tennessee r...', what is the answer? Based on the clue 'a sleeper a hammerlock or an ankle lock', what is the answer? Based on the clue 'a sleuth named kinsey millhone is the heroine of h...', what is the answer? Based on the clue 'a slice of provolone could be mistaken for this ch...', what is the answer?